Ex Parte Bernstein et al - Page 3


               Appeal No.  2004-2221                                              Page 3                
               Application No.  09/731,412                                                              

               acknowledge that Gombotz discloses pore forming agents, they point out that in           
               methods of preparing the microspheres exemplified by Gombotz, there is no                
               mention of a pore forming agent.  See id. at 7.  Thus appellants conclude that           
               “[s]ince Gombotz does not disclose each claimed step, and in particular removal          
               of the pore forming agent with the solvent, . . . Gombotz does not anticipate claim      
               20.”  Id.  We agree.                                                                     
                     The burden is on the examiner to set forth a prima facie case of                   
               unpatentability. See In re Alton, 76 F.3d 1168, 1175, 37 USPQ2d 1578, 1581               
               (Fed. Cir. 1996).  Moreover, in order for a prior art reference to serve as an           
               anticipatory reference, it must disclose every limitation of the claimed invention,      
               either explicitly or inherently.  See In re Schreiber, 128 F.3d 1473, 1477,              
               44 USPQ2d 1429, 1432  (Fed. Cir. 1997).                                                  
                     Gombotz specifically teaches that “[p]ore forming agents are used to add           
               microstructure to the matrices (i.e., water soluble compounds such as inorganic          
               salts and sugars).  They are added as particulates.  The range should be                 
               between one and thirty percent (w/w, polymer).”  Id. at Col. 9, lines 52-55.  The        
               disclosure of a w/w range suggests that the pore forming agents, if added, are           
               retained in the microparticle.  The examiner points to nothing in the reference,         
               and our review of that reference, did not reveal any teaching or suggestion of           
               removing the pore forming agent.  Therefore, the examiner did not meet his               
               burden of setting forth a prima facie case of anticipation, and the rejection is         
               reversed.                                                                                
                                            OTHER ISSUES                                                





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