Ex Parte Trese et al - Page 2



          Appeal No. 2004-2249                                                        
          Application No. 09/820,159                                                  
          of the base claim and any intervening claims.”1  (Examiner’s                
          answer mailed Oct. 21, 2003, paper 17, page 2.)                             
               The subject matter on appeal relates to a “method for                  
          creating a separation of posterior cortical vitreous in an eye              
          from an eye retina.”  According to the appellants, “[c]ertain               
          diseases and/or conditions of the eye, such as diabetes, cystoid            
          macular edema or trauma, produce a vitreoretinal traction on the            
          surface of the retina,” which, if continued, “may lead to breaks            
          in the retinal surface and, in severe cases, to retinal                     
          detachment.”  (Specification, page 1, lines 9-12.)  The                     
          appellants further explain that “[t]he introduction of plasmin              
          into the vitreous humor creates a separation of the posterior               
          cortical vitreous and the retina thus minimizing or eliminating             
          the vitreoretinal traction.”  (Id. at page 1, lines 21-23.)  The            
          appellants also disclose that “if additional plasmin is                     
          necessary to create the desired separation between the vitreous             
          16 and the retina 14, a portion of the aqueous humor 16 may be              
          removed from the anterior chamber 32 [sic] by paracentesis to               
          eliminate excessive intraocular pressure.”  (Id. at page 3,                 
                                                                                     
               1  The final rejection under 35 U.S.C. § 112, ¶1 (lack of              
          written description), of claims 3 and 4 has been expressly                  
          withdrawn.  (Answer at 5.)                                                  

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