Ex Parte Dey et al - Page 4


               Appeal No. 2005-0317                                                                         Page 4                  
               Application No. 09/962,352                                                                                           

               166 USPQ 545, 548 (CCPA 1970) (“[E]very limitation positively recited in a claim must                                
               be given effect in order to determine what subject matter that claim defines.”); In re                               
               Angstadt, 537 F.2d 498, 501, 190 USPQ 214, 217 (CCPA 1976) (“[W]e must give effect                                   
               to all claim limitations.”).                                                                                         
                       Here, the claims are directed to a “method . . . comprising administering . . . an                           
               effective antineoplastic amount of 17α-dihydroequilin . . . in substantially purified form.”                         
               The examiner’s claim interpretation effectively reads out the final limitation from the                              
               claim.  That is, under the examiner’s interpretation, the claim is open to administration of                         
               17α-dihydroequilin in combination with other estrogens.  Under this interpretation, the                              
               claim would have the same scope as one that read a “method . . . comprising                                          
               administering . . . an effective antineoplastic amount of 17α-dihydroequilin.”                                       
                       As Appellants have pointed out, their interpretation of the claim language is                                
               supported by the working examples in the specification, which involve administration of                              
               17α-dihydroequilin without any other estrogens.  It is also supported by the prosecution                             
               history, during which Appellants have consistently interpreted the claim to require                                  
               administering 17α-dihydroequilin in “substantially purified form, i.e., substantially free of                        
               other estrogenic components.”  See, e.g., the response filed September 17, 2002, page                                
               7.  Both the specification and the prosecution history are relevant to construing claim                              
               language.  See Renishaw plc v. Marposs Societa per Azioni, 158 F.3d 1243, 1248, 48                                   
               USPQ2d 1117, 1120 (Fed. Cir. 1998) (“[A] claim must be read in view of the                                           
               specification of which it is a part.”); id. at 1249 n.3, 48 USPQ2d at 1121 n.3 (“Likewise,                           
               any interpretation that is provided or disavowed in the prosecution history also shapes                              
               the claim scope.”).                                                                                                  





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