Appeal No. 2005-0978 Application No. 09/983,232 35 U.S.C. § 103 Claims 54-56 stand rejected under 35 U.S.C. §103(a), as unpatentable over Petterson. In rejecting claims under 35 U.S.C. § 103, the examiner bears the initial burden of presenting a prima facie case of obviousness. See In re Rijckaert, 9 F.3d 1531, 1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993). It is well-established that the conclusion that the claimed subject matter is prima facie obvious must be supported by evidence, as shown by some objective teaching in the prior art or by knowledge generally available to one of ordinary skill in the art that would have led that individual to combine the relevant teachings of the references to arrive at the claimed invention. See In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988). According to the examiner (Answer, page 4): Pettersen et al. teach a method of inhibiting the growth of a cancer cell (e.g. lung carcinoma) in which the method comprises contacting the cancer cell with a pharmaceutical composition comprised of compounds defined by formula l (see Col. 2, lines 40-67; Col. 3 thru Col. 4, lines 1-29; Col. 16 and 17). The difference between the presently claimed invention and what is taught by the Petterson et al. reference is that the Pettersen et al. reference does not specifically recite compounds according to Formula II A of the present claims. However, Pettersen et al. do generally teach a group of compounds, represented by their formula I, in which some of the presently claimed species are encompassed. The examiner concludes “[i]t would have been prima facie obvious to one having ordinary skill in the art, in view of the Pettersen et al. reference, to arrive at the presently claimed invention because Pettersen et al. teach a similar method of inhibiting the growth of a cancer cell with a group of compounds is [sic, in] which some of the possible 5Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007