Ex Parte Saito et al - Page 7


                Appeal No. 2005-1442                                                                                 Page 7                    
                Application No. 09/734,786                                                                                                     

                was not nonenabled merely because it encompassed one difficult-to-achieve outcome.                                             
                The same reasoning applies here:  the examiner may be correct that achieving clinically                                        
                useful gene therapy using the claimed method would require undue experimentation,                                              
                but the claims are not nonenabled merely for encompassing that  difficult-to-achieve                                           
                outcome.                                                                                                                       
                         The claims are directed to methods of introducing a nucleic acid into a                                               
                mammalian subject or delivering a nucleic acid to a hair follicle or intact tissue.  The                                       
                examiner has not adequately explained why the specification does not enable those                                              
                skilled in the art to introduce a nucleic acid into a mammalian subject, or deliver a                                          
                nucleic acid to a hair follicle or intact tissue, without undue experimentation.  We                                           
                therefore reverse the rejection for nonenablement.                                                                             


                                                               REVERSED                                                                        



                                          Joan Ellis                               )                                                          
                                          Administrative Patent Judge               )                                                          
                                                                                    )                                                          
                                                                                    )                                                          
                                                                                    ) BOARD OF PATENT                                          
                                          Toni R. Scheiner                         )                                                          
                                          Administrative Patent Judge               )   APPEALS AND                                            
                                                                                    )                                                          
                                                                                    ) INTERFERENCES                                            
                                                                                    )                                                          
                                          Eric Grimes                              )                                                          
                                          Administrative Patent Judge               )                                                          


                EG/dym                                                                                                                         





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