Ex Parte BORNSCHEUER et al - Page 18




              Appeal No. 2005-1745                                                                                     
              Application No. 09/161,680                                                                               


              1572, 41 USPQ2d at 1966).  As still further discussed above, it is not necessary for the                 
              specification to describe the claimed invention ipsissimis verbis; all that is required is that          
              it reasonably convey to those skilled in the art that, as of the filing date sought, the                 
              inventor was in possession of the claimed invention.  Union Oil of California v. Atlantic                
              Richfield Co., 208 F.3d at 997, 54 USPQ2d at 1232; Vas-Cath Inc. v. Mahurkar, 935                        
              F.2d at 1563-64, 19 USPQ2d at 1119; In re Gosteli, 872 F.2d at 1012, 10 USPQ2d at                        
              1618; In re Edwards, 568 F.2d at 1351-52,196 USPQ at 467.                                                
                     Here, as indicated above, we find that the specification, as originally filed, does               
              not provide any description of using the claimed method to generate a new catalytic                      
              activity for an acylase.  Accordingly, we find that claims 20 and 26 fail to comply with the             
              written description requirement of 35 U.S.C. § 112.                                                      
                     B.  Claims 12-26                                                                                  
                     Claims 12-26 are rejected under 35 U.S.C. § 112, first paragraph, as containing                   
              subject matter which was not described in the specification in such a way as to                          
              reasonably convey to one skilled in the relevant art that the inventors had possession of                
              the claimed invention at the time the application was filed.                                             
                     As discussed above, the specification, as originally filed, does not provide an                   
              adequate written description of a method “for generating a new catalytic activity in an                  
              enzyme.”                                                                                                 
                     Enzymes are proteins that act as catalysts.  “The chemicals that undergo a                        

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