Ex Parte Schilling et al - Page 6


                   Appeal No. 2005-2120                                                                  Page 6                      
                   Application No. 09/964,120                                                                                        

                   and furthermore, does not teach or suggest combining the protein with at least                                    
                   15% by weight of an ionizing salt.                                                                                
                           Steffan, however, is drawn to a method of manufacturing collagen fibers                                   
                   for surgical application.  See Col. 1, lines 8-10.  While as noted by the examiner,                               
                   sodium chloride in an amount between 5 to 15% weight percent is used in the                                       
                   dehydration processes, see Col. 3, lines 32-34, before that, the collagen is                                      
                   subject to alkali treatment, acidification using hydrochloric acid to a pH less than                              
                   2, and mechanical treatment, see Col. 2, line 50-Col. 3, line 20, processes which                                 
                   are not designed to preserve the chemical, physical, and physiological properties                                 
                   of the protein.  As such preservation of properties is an important object of the                                 
                   methods of Moore and Luck, the ordinary artisan would not look to Steffan for the                                 
                   addition of salt to the dehydration processes of those references to arrive at the                                
                   claimed invention.                                                                                                
                           Claims 42-50 stand rejected under 35 U.S.C. § 103(a) as being obvious                                     
                   over the combination of Moore and Ota.                                                                            
                           Moore is relied upon as above.  The examiner acknowledges that “Moore                                     
                   does not specify the water content” and “does not teach adding salt.”  Examiner’s                                 
                   Answer, page 10.                                                                                                  
                           Ota is cited for teaching a method of dehydrating scallops using salt.  In                                
                   the method, 7-15% salt is used to dehydrate the ligaments of the scallops, and,                                   
                   as noted by the rejection, “ligaments inherently contain collagen I.”  Id.                                        
                           The rejection concludes:                                                                                  







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