Appeal No. 2005-1535 Application No. 10/049,379 In view of the above, we agree with appellants that the examiner has failed to provide evidence to support a prima facie case of obviousness. Nor does the examiner provide motivation for combination of the cited references. The examiner has not indicated why one of ordinary skill in the art would have been motivated to incorporate glycerol into an oxaliplatinum composition. In our view, while Schlipalius relates to an intravenous composition comprising glycerol, Schlipalius does not suggest that adding glycerol to oxaliplatinum would increase their concentration or solubility while maintaining shelf life. While Schlipalius may have indicated to one of ordinary skill in the art that beta carotene could be delivered intravenously in glycerol, in view of the solubility spectrum of oxaliplatinum as set forth in the specification, we do not find Schilpalius provides motivation to deliver oxaliplatinum in glycerol or that one of ordinary skill in the art would have been motivated to do so with an expectation of success. In view of the above, the rejection of the claims for obviousness over Ibrahim in view of Schlipalius is reversed. CONCLUSION The rejection of claims 1-11 and 15-17 for obviousness over Ibrahim and Schlipalius is reversed. 7Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007