Appeal No. 2005-2446 Page 6 Application No. 09/951,099 According to Dawson, “suitable hydratable polysaccharides are the galactomannan gums, glucomannan gums, guars, derived guars and cellulose derivatives” (id., column 3, lines 21-24). “Suitable enzyme breakers include, for example, the cellulases . . . [which] specific[ally] [ ] degrade the particular polymeric linkage found on the polysaccharide polymer backbone of the crosslinked gel, for instance, the 1,4 linkage between mannose in galactomannans” (id., column 4, lines 11-21). Finally, according to Dawson, “[a]ny conventional buffer can be used to adjust the pH, for instance aqueous potassium carbonate” (id., column 5, lines 1-2). The examiner acknowledges that “Dawson differs from the claims in not disclosing the use of . . . ‘Tris’[ ] as the buffer in the [alkaline] pH adjustment step” (Examiner’s Answer, page 4), but relies on Segel’s list of “acids and bases that are useful in preparing buffers for enzyme assays” as evidence that “Tris is an extremely well known buffer, conventionally used in processes employing enzymes” (id.). Moreover, the examiner notes that Tris “has an alkaline pKa of 8.1 and is therefore capable of providing buffering power in the alkaline range initially required in Dawson’s fracturing fluid” (id.).4 According to the examiner, “the artisan of ordinary skill clearly would have recognized Tris as being a conventional buffer suitable for processes employing enzymes, [thus,] the claimed substitution of Tris into Dawson’s process must be . . . considered obvious” (id., pages 4 and 5). Appellants argue that the examiner’s conclusion is unfounded because, among other things, “[t]he only specific reference to Tris buffer systems having a particular pH in 4 We note that the pKa value provided here is for Tris at 25°.Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007