Ex Parte Knapp - Page 9


                Appeal No. 2005-2690                                                                                                         
                Application No. 09/935,442                                                                                                   

                that one of ordinary skill in the art confronted with the same problems as the inventor, i.e.                                
                prevention of restenosis upon stent implantation, and with no knowledge of the claimed                                       
                invention, would select the elements from the cited prior art references for combination in                                  
                the manner claimed, to support a prima facie case of obviousness.  We do not find that                                       
                the evidence before us provides such motivation or evidences that one of ordinary skill in                                   
                the art would have expected that the incorporation of a separately released fibrinogen                                       
                and thrombin for conversion to an activated fibrin form for local delivery into an adapted                                   
                medical device which is a vascular catheter, a vascular stent or a vascular graft, would                                     
                have addressed clotting problems associated with the fibrin formation upon stent                                             
                implantation and would have addressed issues associated with restenosis upon stent                                           
                implantation.   The rejection of claims 1-6, 8-13, 15, 26-28, and 47-52 over Dinh in view                                    
                of Delmotte and Sawhney is reversed.                                                                                         





                                                             CONCLUSION                                                                      
                        The rejection of claims 1-6, 8-13, 15, 26-28, and 47-52 under 35 U.S.C. § 103 for                                    
                obviousness over Dinh in view of Delmotte and Sawhney is reversed.                                                           
                        No time period for taking any subsequent action in connection with this appeal                                       
                may be extended under 37 CFR § 1.136(a).                                                                                     


                                                               REVERSED                                                                      



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