Ex Parte Schnellmann et al - Page 3


                Appeal No. 2006-0872                                                   Page 3                  
                Application No. 09/899,704                                                                     

                      healing such as proliferation following injury, including eye injury,                    
                      that is caused by a variety of conditions, including toxic substances.                   
                Examiner’s Answer, page 4.                                                                     
                      “In rejecting claims under 35 U.S.C. § 103, the examiner bears the initial               
                burden of presenting a prima facie case of obviousness.  Only if that burden is                
                met, does the burden of coming forward with evidence or argument shift to the                  
                applicant.”  In re Rijckaert, 9 F.3d 1531, 1532, 28 USPQ2d 1955, 1956 (Fed. Cir.               
                1993) (citations omitted).  We find that the examiner has met that burden, and                 
                the rejection is affirmed.  Moreover, as we find that the Fahim reference alone                
                renders the invention of claim 11 unpatentable, we further focus our analysis on               
                that reference.                                                                                
                      Claim 11 is drawn to:                                                                    
                      A method of recovering cellular functions following injury in an individual in           
                need of treatment, comprising the steps of:                                                    
                      administering a therapeutically effective amount of ascorbic acid or a salt              
                of ascorbic acid to said individual,                                                           
                      wherein said cellular functions are selected from the group consisting of                
                proliferation, mitochondrial function, Na+-K+-ATPase protein expression, Na+-K+-               
                ATPase protein activity, and active Na+ transport.                                             
                      Fahim teaches a composition for promoting epithelial regeneration, i.e.,                 
                proliferation,2 see id. at Col. 1, lines 11-13, wherein the composition comprises a            
                mixture of vitamin C (ascorbic acid), zinc and sulfur amino acid, see id. at Col. 1,           


                                                                                                               
                2 Note that claim 1 of Fahim is drawn to “A medication for treating epithelial tissue comprising
                vitamin C, a zinc salt and a sulfur amino acid in an amount sufficient to stimulate cell proliferation
                and new cell formation.”                                                                       





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