Appeal No. 2006-1083 Page 4
Application No. 09/799,251
deficiency anemia, folic acid to prevent neural tube defects, [and] compounds to reduce
serum homocysteine and improve the lipid profile” (id., lines 57-62). In addition,
phytoestrogens, “a class of isoflavones or isoflavenoids derived from plants, commonly
soy beans” (id., column 4, lines 65-67), “are included in each of the dietary supplements”
(id., lines 51-54). In addition, the dietary supplements may optionally contain provitamin
A carotenoids, like cryptoxanthin, and/or non-provitamin carotenoids, such as lutein and
lycopene (id., column 6, line 63 to column 7, line 5). According to Jackson,
phytoestrogens “modulate the menstrual cycle, reduce menopausal symptoms, and
lower LDL cholesterol levels” (id., column 4, lines 53-55), moreover, “diets rich in
phytoestrogen[s] . . . [result in] a decreased incidence of breast cancer, menopausal
symptoms and osteoporosis” (id., lines 57-59), while lycopene “has been inversely
associated with the risk of cervical cancer” (id., column 7, lines 7-8).
Shlyankevich describes dietary supplements “effective in the prevention of the
onset of clinical manifestations of osteoporosis” (Shlyankevich, column 3, lines 12-13).
The supplements comprise at least eight “active ingredients” (id., lines 15-16), including
phytoestrogens, licorice root extract, calcium, magnesium, zinc, beta-carotene,
cholecalciferol, and vitamin E (id., lines 18-31). Shlyankevich teaches that
phytoestrogens “have the ability to improve hormonal balance, [ ] are highly effective in
the treatment of osteoporosis” (id., column 5, line 68 to column 6, line 1), and are
“associated with the reduction of free plasma estradiol, and the risk of breast cancer” (id.,
column 2, lines 58-61). Thus, “[n]atural dietary phytoestrogens can replace estrogen
therapy” (id., column 5, lines 65-66), without the “side effects and other risk factors
associated with using estrogens . . . to prevent postmenopausal osteoporosis” (id.,
Page: Previous 1 2 3 4 5 6 7 8 Next
Last modified: November 3, 2007