Ex Parte Jiang et al - Page 6



         Appeal No. 2006-1728                                       Παγε 6                          
         Application No. 10/337,417                                                                 

         Faithfull for a teaching of an apparatus for administering                                 
         fluorocarbon to the lungs of a patient during partial liquid                               
         ventilation.  Faithfull specifies that the fluorocarbon is                                 
         administered by a nebulizer (98) in the form of a mist, to be                              
         readily absorbed in the alveolar lung tissue.  The examiner                                
         asserts (answer, page 4) that “[i]t appears that the average size                          
         of the nebulized liquid particles must be less than 5 microns,”                            
         and that “it appears that the mist comprises less than 20% liquid                          
         by volume”.  The examiner additionally takes the position                                  
         (answer, pages 5 and 6) that the disclosure of Schutt (col. 10,                            
         lines 24-25) “fluorocarbon could also be provided as a liquid or                           
         aerosol in combination with an expectorant” makes a clear                                  
         suggestion that the procedure could be performed with a mist.                              
         The examiner additionally relies upon the Michaels (‘854) patent                           
         as evidence that nebulizers are capable of producing particles                             
         having a size of less than 5 microns, or less than 2 microns so                            
         that the particles can deposit in the alveoli of the lungs.  The                           
         examiner relies upon the Michaels (‘002) patent as evidence that                           
         nebulizers are well known for producing mists that have at least                           
         80% gas by volume.                                                                         
              Appellants' position (brief, page 4) is that the cited                                
         references, even if combined, do not suggest using partial liquid                          













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