Appeal No. 2006-1742
Application No. 10/001,439
acknowledges that infants develop gastroenteritis about the time they are
weaned from breast milk and placed on formula. Column 1, lines 51-62. Thus,
Paul would reasonably appear to suggest a powdered composition comprising
lactoferrin, guar gum, citrus pectin and immunoglobulins derived from colostrum
that is appropriate for use in infants to prevent gastroenteritis.
Plaut similarly describes infant formulas comprising colostrum
(pasteurized milk) and lactoferrin. Plaut, page 3. Plaut indicates that antibodies
from colostrum are known to protect children from infection by several
gastrointestinal pathogens. Page 2. Plaut suggests that colostrum may be used
or antibodies can be purified from milk and combined with lactoferrin as used as
a formula additive. Page 6, lines 15-18. In the regard, we note that Plaut
discloses that the formula preferably includes colostrum. Plaut, page 5, lines 9-
11. Finally, Donzis describes that glucan extracted from yeast cell walls is a
potent stimulator of the immune system (Column 1, lines 20-21) and
recommends that beta (1,3) glucans be incorporated as a nutritional supplement
for a broad spectrum of animals and humans. Column 1, lines 52-67. Donzis
indicates that beta glucan strongly enhances resistance to diseases, both viral
and bacterial, and enhances growth rate, survival rate and feed efficiency.
Column 3, lines 15-27.
It would have been obvious to one of ordinary skill in the art at the time of
the invention to substitute the colostrum of the infant formulas of Plaut
comprising immunoglobulins, for the immunoglobulins derived from bovine
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