Ex Parte Alocilja et al - Page 8


              Appeal No. 2006-2198                                                                  Page 8                 
              Application No. 10/074,499                                                                                   

              3.  Obviousness based on Kim, Sigal, and Roberts                                                             
                     The examiner also rejected claims 3, 10, 22, 24, and 26 under 35 U.S.C. § 103                         
              as obvious in view of Kim, Sigal, and Roberts.3  The examiner relied on Kim and Sigal                        
              for the disclosures discussed above, but acknowledged that neither reference teaches a                       
              multiple array.  The examiner cited Roberts for its disclosure of “multiple sets of                          
              interdigitated electrode arrays . . . in order to perform simultaneous multiple analyte                      
              detection and assay a test sample for a plurality of analytes.”  Examiner’s Answer,                          
              pages 7-8.  The examiner concluded that “[i]t would have been obvious at the time of                         
              the invention to modify the method of Kim et al[.] and Sigal et al[.] with a test device that                
              includes multiple sets of interdigitated electrode arrays . . . as taught by Roberts et al[.],               
              in order to perform simultaneous multiple analyte detection and assay a test sample for                      
              a plurality of analytes.”  Id., page 8.                                                                      
                     We agree with the examiner that the device of claim 22 would have been prima                          
              facie obvious in view of the cited references.  As discussed above, Kim and Sigal show                       
              that the device of claim 1 would have been obvious to those of ordinary skill in the art.                    
              Claim 22 is directed to the same device, “as a multiple array of devices grouped                             
              together separately on the substrate so that multiple analytes can be detected                               
              simultaneously from the same sample.”                                                                        
                     Roberts discloses an immunoassay device in which the signal is measured                               
              electrochemically.  See column 5, line 55 to column 6, line 30.  Roberts also teaches                        
              that “[w]ith the test devices and methods of the invention, one may also assay a test                        
              sample for a plurality of analytes such as toxic chemicals, or screen for one or more of a                   
                                                                                                                           
              3 Roberts et al., U.S. Patent 5,958,791, issued Sept. 28, 1999                                               





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