Appeal No. 2006-2627 Page 2 Application No. 09/947,833 Background “Calcium sulfate has been clinically used for many years as a bone void filler with successful results.” Specification, page 1. Calcium sulfate hemihydrate is also known as Plaster of Paris. See Yim,2 column 2, lines 60-62. The specification discloses a “bone graft substitute composition . . . [that] comprises, in general, a quantity of calcium sulfate, a quantity of fluid (e.g., sterile water), and a quantity of a plasticizing substance (e.g., methylcellulose) which provides a resultant composition that is robust and has an extended set time.” Specification, page 3. The “extended set time . . . provides a useful working time of at least 5 minutes to allow sufficient time for a surgeon to properly apply the bone graft substitute composition, while the robustness of the resultant composition allows the implanted composition to withstand the typical pressure of body fluids, irrigation fluids and/or suctioning with minimal material erosion, disintegration or dissolution.” Id. “The composition may include a bioactive agent selected from the group consisting of demineralized bone matrix, growth factors, hyaluronic acid, bone morphogenic proteins, bone autograft, and bone marrow, etc.” Id., page 4. Discussion 1. Claims Claims 1-26 are pending and on appeal. Claim 1 is representative and reads as follows: 1. A bone graft substitute composition, comprising: about 80 to about 120 parts by weight of calcium sulfate; 2 Yim et al., U.S. Patent No. 5,385,887, issued January 31, 1995 (of record).Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007