Appeal No. 2006-2627 Page 43 Application No. 09/947,833 According to appellants (Brief, page 12), nothing in Wironen “the only reference that even mentions cancellous bone . . . direct[s] one of ordinary skill in the art to [a]ppellants’ claimed . . . method . . . .” However, as discussed above, the only process step required by the method of claim 25 does not require multiple separate portions of a composition containing cancellous bone. To the contrary, the method simply requires that a single portion of a composition comprising calcium sulfate, demineralized bone, hydroxypropyl methylcellulose and cancellous bone be mixed with a mixing solution. As discussed above, the combination of O’Leary, Yim and Wironen teach a method of repairing bone injury wherein a composition comprising calcium sulfate, demineralized bone, hydroxypropyl methylcellulose and cancellous bone within the scope of appellants’ claim 25 is mixed with a mixing solution. Accordingly, I would affirm the rejection of claim 25 under 35 U.S.C. § 103(a) as being unpatentable over the combined teachings of O’Leary, Yim and Wironen. As discussed supra claim 26 falls together with claim 25. Majority opinion: Rigidly applying the suggestion test and failing to consider all the evidence of record, the majority concludes (Supra, page 10), “[t]he examiner has not adequately explained how the prior art would have suggested modifying O’Leary’s composition by adding calcium sulfate to it.[ ]44 Nor has the examiner provided a rationale based on the knowledge of those of skill in the art or the nature of the problem to be solved.” 44 While the majority recognizes (supra, bridging sentence, pages 7-8), “Yim’s compositions have two required components: calcium sulfate hemihydrate-containing substance (CSHS) and an osteogenicPage: Previous 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 NextLast modified: November 3, 2007