Ex parte MOROZUMI et al. - Page 4




          Appeal No. 95-3056                                                           
          Application 07/833,718                                                       
          rendered commercially impractical because [of] the instability               
          of hydrated 2-octynyladenosine when stored” (Ans., pp. 6-7,                  
          bridging para.).                                                             
               F.   The examiner finds that “it does not defy logic . .                
          . that a compound of known chemical structure, initially                     
          isolated in hydrated form, should not be patentably                          
          distinguishable from the identical compound rendered anhydrous               
          by one or more conventional purification steps” (Ans., p. 6,                 
          l. 9-13).                                                                    
               G.   The examiner finds that applicants have solved “a                  
          very simple problem quickly understood by any ordinary                       
          practitioner using commonly available analytical techniques .                
          . . and quickly soluble [sic] using routine purification                     
          techniques” (Ans., p. 7, l. 6-10).                                           
               H.   The examiner finds that “pharmaceuticals are                       
          routinely tested for activity as a function of storage                       
          conditions to determine how they must be processed in                        
          preparation for storage” (Ans., p. 7, l. 13-15).                             
               I.   The examiner finds that “[i]nstability in the                      
          presence of retained solvent, i.e. herein water of hydration,                
          is not unheard of and . . . readily soluble [sic] in several                 
          different ways without undue expense” (Ans., p. 7, l. 16-18).                
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