Ex parte CALLAGHAN et al. - Page 3




          Appeal No. 96-2179                                           Page 3           
          Application 07/613,466                                                        
               3.   At the hearing, counsel confirmed that Pacesetter                   
          Inc. is the real party in interest.                                           
               4.   The application is entitled "Rate-responsive                        
          pacemaker with closed-loop control".  The subject matter of                   
          the invention is means and steps for regulating pacing with                   
          respect to a measured rate control parameter (MRCP) and                       
          adjusting the pacing rate to account for variations in the                    
          MRCP.  Claims 38 and 49 (Paper 17 (Prelim. Amdt.) at 2-3)                     
          illustrate the subject matter of the invention:                               
                    38. A method of controlling rate-responsive                         
               pacing comprising the steps of periodically                              
               ascertaining the value of a rate control parameter                       
               "RCP" to obtain a measured rate control parameter                        
               "MRCP", said RCP being such that a measured value                        
               thereof is changed in one direction by increases in                      
               stress/exercise and in an opposite direction by                          
               increases in heart rate, generating pacing pulses at                     
               a pacing rate, deriving a target value "target"                          
               which is indicative of changes in said MRCP due to                       
               non-stress/exercise and non-heart rate factors, and                      
               responsive to a change in the difference between                         
               MRCP and target adjusting said pacing rate in a                          
               direction which tends to return said difference to                       
               its pre-change value.                                                    
                    49. A method of controlling rate-responsive                         
               pacing comprising the steps of generating pacing                         
               pulses at a pacing rate, ascertaining the value of a                     
               rate control parameter "RCP", utilizing closed-loop                      
               control for adjusting said pacing rate in accordance                     
               with the value of said RCP, and causing said closed-                     
               loop control to self-adapt to changes in the value                       
               of said RCP which are due to factors other than                          
               stress, exercise and heart rate.                                         







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