Appeal No. 96-2179 Page 5
Application 07/613,466
3-7, 14-18, 20-24, 28, Nappholz and Callaghan
30-33, and 35-37 '900;
42, 43, 45-48, 52-57, Nappholz and Callaghan
and 59-61 '900;
8-11 and 19 Nappholz, Callaghan '900,
and Mumford; and
44 Nappholz and Mumford.
C. The meaning of terms
12. We agree with the examiner that there is an apparent
inconsistency in a measured parameter that changes in one
direction in response to increased stress or exercise and in
an opposite direction in response to increased heart rate.
Daily experience suggests an increase in stress or exercise
routinely corresponds to an increase in heart rate in a
normally functioning heart. Appellants' specification
discloses the depolarization gradient lends itself to rate4
control in a closed loop because increased emotional or
physical stress and increased heart rate have opposite effects
on this parameter. (Paper 1 at 13.) The specification
continues, however, to explain that this effect appears when
either workload or pacing rate are held constant. (Paper 1
4 The integral of the evoked potential. (Paper 1
at 1; Figs. 5 & 6.)
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Last modified: November 3, 2007