HUANG et al. V. PRASIT et al. - Page 13




                    I have carefully studied, the Bertenshaw                          
               Application USSN 08/425,029 (DE 61, pages 0146-                        
               0233), and in vitro assays used therein, and the                       
               Declaration for Ducharme of Dr. A. Jerry Kresge (DE                    
               6), and based on that study I have found the                           
               following:                                                             

                    29. Huang argues that the testimony of the Merck                  
          witnesses relate to problems with in vitro testing in general               
          and is applicable to all compounds regardless of their                      
          structure (Paper 47 at 6).                                                  
                    30.       Huang argues that Merck should be bound by              
          its admissions in the '845 or '873 interferences under                      
          principles of judicial estoppel (Paper 47 at 6).                            
                                      Priority                                        
                    31. Prasit relies upon the 29 August 1994 filing                  
          date of its benefit application, 08/297,461.  Prasit argues                 
          that Huang has not established a date of invention prior to                 
          the 29 August 1994 filing date (Paper 49 at 1).                             
                    32. Huang argues that it "has established a date of               
          invention, i.e., an actual reduction to practice, of the                    
          subject matter defined by the interference count at least as                
          early as September 28, 1993" (Paper 46 at 1).                               
                    33. According to Huang, on 2 September 1993,                      
          inventor Dr. Horng-Chih Huang entered, in his notebook,                     

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