(5) CN,
(6) CF ,
3
(7) C alkyl,
1-6
(8) N ,
3
(9) -CO H,
2
(10) -CO -C alkyl,
2 1-4
(11) -C(R )(R )-OH,5 6
(12) -C(R )(R )-O-C alkyl, and5 6 1-4
(13) -C alkyl-CO -R ;7
1-6 2
(d) mono- or di-substituted heteroaryl
wherein the heteroaryl is a monocyclic aromatic ring
of 5 atoms, said ring having one hetero atom which
is S, O, or N, and optionally 1, 2, or 3 additional
N atoms; or the heteroaryl is a monocyclic ring of 6
atoms, said ring having one hetero atom which is N,
and optionally 1,2,3, or 4 additional N atoms; said
substitutents are selected from the group consisting
of
(1) hydrogen,
(2) fluoro, chloro, bromo and iodo,
(3) C alkyl,
1-6
(4) C alkoxy,
1-6
(5) C alkylthio,
1-6
(6) CN,
(7) CF ,
3
(8) N ,
3
(9) -C(R )(R )-OH, and5 6
(10) -C(R )(R )-O-C alkyl;5 6 1-4
(e) benzoheteroaryl which includes the
benzo fused analogs of (d);
7
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Last modified: November 3, 2007