Ex parte MCCAFFREY et al. - Page 5




              Appeal No. 94-4393                                                                                          
              Application 07/692,921                                                                                      


                     Here, it appears that the examiner considered the definiteness of the word                           
              “subspecies” in a vacuum.  This is incorrect.  Rather, the examiner must analyze the                        
              supporting disclosure of this application and relevant prior art, e.g., the twelve references               
              cited in the Amendment After Final rejection (Paper No. 18, September 3, 1993).                             
                     The examiner should also note that claims 9 through 13 do not use the word                           
              “subspecies” but rather, are directed to so-called heparin fractions.  The examiner has not                 
              found the word “fraction” to be indefinite.  It appears from reading the specification of this              
              application that appellants use the two words interchangeably.  If so, since the examiner                   
              has no apparent problem with appellants using the word “fraction,” this issue might be                      
              simply resolved by the examiner allowing appellants to amend the relevant claims to use                     
              the word “fraction” or “fractions” instead of the objected to word “subspecies.”                            


                                             Adequacy of Prior Art Search                                                 
              1.  Classes and Subclasses.                                                                                 
                     The “SEARCHED” portion of the file jacket of this application indicates that a single                
              class and subclass, Class 530, Subclass 328, has been searched by the examiner.  That                       
              subclass appears to be most relevant to the 10 amino acid polypeptide set forth in claim 6                  
              on appeal.  It does not appear that the examiner’s search of the classes and subclasses                     
              took into account all of the claims on appeal.  It would appear that classes and subclasses                 


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