Ex parte GOLDENBERG - Page 5




          Appeal No. 95-0206                                                          
          Application 07/866,789                                                      


          (1988); Ashland Oil, Inc. v. Delta Resins & Refractories, Inc.,             
          776 F.2d 281, 293, 227 USPQ 657, 664 (Fed. Cir. 1985), cert.                
          denied, 475 U.S. 1017 (1986); ACS Hospital Systems, Inc. v.                 
          Montefiore Hospital, 732 F.2d 1572, 1577, 221 USPQ 929, 933 (Fed.           
          Cir. 1984).  These showings by the examiner are an essential part           
          of                                                                          
          complying with the burden of presenting a prima facie case of               
          obviousness.  Note In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d            
          1443, 1444 (Fed. Cir. 1992).                                                
          In rejecting claim 1, the examiner noted that Goldenberg                    
          ‘647 taught a method for detecting and localizing tumors using              
          radiolabeled antibodies specific to antigens which are produced             
          or associated with the tumor.  According to the examiner, the               
          only features not taught by Goldenberg ’647 were the emitting               
          energy of the radioisotope [recited in claim 3] and the specific            
          immunoreactivity of the antibody or fragment and the cross-                 
          reactivity to other antigens [recited in claim 7] [answer, page             
          3].  The examiner relied on Hansen for teaching the claimed                 
          emitting energy of the radioisotope and relied on Goldenberg ‘544           
          for teaching the claimed immunoreactivity and cross-reactivity to           
          other antigens.                                                             



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