Appeal No. 95-3830 Application No. 07/942,460 We can observe no basis for the examiner's finding (answer at 3) that: The ultrafiltrate monitor (Fig. 2) uses the data from the [pressure] sensors to calculate the membrane clearance for ultrafiltrate impurity. The UF control 124 controls the flow rate as claimed. The ultrafiltrate rate is related to the transmembrane pressure. Figure 2 of Shouldice et al. merely shows that data from pressure sensors 94 and 96 are inputted to the ultrafiltrate monitor 130. We find no discussion anywhere in Shouldice et al. concerning calculation of a clearance for "a type of impurity" based on the data from pressure sensors 94 and 96, and the examiner has cited none. The closest Shouldice et al. comes to that is the following (column 5, lines 9-13): A TMP (transmembrane pressure) that is too high indicates that the operator is trying to pull too much ultrafiltrate (in which event he can lower the ultrafiltration rate) or that the membrane is clogged (in which event use of the clogged dialyzer must be discontinued). Shouldice et al., in column 3, lines 13-14, defines the term "ultrafiltrate" as that liquid passing through the membrane in dialyzer 20 from blood to dialysate. Transmembrane pressure is not the same as either the fresh dialysis liquid pressure or the used dialysis liquid pressure as measured by pressure sensors 94 and 96. Even assuming that the transmembrane pressure can be -6-Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007