KEITH et al. V. COELHO - Page 19




          Interference No. 103,270                                                    



          Keith et al., would make the proximal end of the guidewire                  
          inaccessible and prevent a physician from holding the                       
          guidewire in position and inflating the guidewire balloon                   
          (KOB-87 to 93).                                                             
                    We do not agree that this alleged inoperativeness                 
          vitiates CX-65 and 66 as evidence of conception.  As pointed                
          out by Coelho at CB-64 to 66, many of the dimensions employed               
          by                                                                          
          Keith et al. in their calculations are disclosed as                         
          approximate                                                                 
          or typical, not rigid.  Moreover, and more fundamentally,                   
          there                                                                       


          is conception when the invention is defined in the inventor's               
          mind such that only ordinary skill would be necessary to                    
          reduce it to practice, without extensive research or                        
          experimentation.  Burroughs Wellcome Co. v. Barr Labs., Inc.,               
          40 F.3d 1223, 1228, 32 USPQ2d 1915, 1919 (Fed. Cir. 1994),                  
          cert. denied, 515 U.S. 1130 (1995).  It seems evident to us                 
          that one of ordinary skill putting into practice the method                 
          conceived by Coelho would design the lengths and positions of               
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