Ex parte REYES et al. - Page 3




              Appeal No. 94-0120                                                                                          
              Application 07/208,512                                                                                      




                     converting the strand/primer complexes to double-strand fragments in the presence                    
              of polymerase and deoxynucleotides, and                                                                     
                     repeating said denaturing, hybridizing, and converting steps until a desired degree                  
              of amplification is achieved.                                                                               
                     The references relied upon by the examiner are:                                                      
              Mullis et al. (Mullis)                     4,683,195                    July 28, 1987                       
              Eur. Pat. App. (Van de Sande)              0 224 126                    June 3, 1987                        
              Maniatis et al. (Maniatis), “Strategies for cDNA Cloning”, Molecular Cloning: A Laboratory                  
              Manual, 227-28 (1982).                                                                                      
                     Claims 1 through 14 stand rejected under 35 U.S.C. § 103 as unpatentable over                        
              Van de Sande taken with Mullis and Maniatis.  We reverse.                                                   
                                                     DISCUSSION                                                           
                     Appellants state at page 3 of the appeal brief that the claims stand or fall together                
              for the purposes of this appeal.  In stating the rejection on pages 2-5 of the examiner’s                   
              answer, the examiner has rejected the claims as a group and has not applied the                             
              teachings of any specific reference to the requirement of any specific claim.                               
              We make this point since it appears that the examiner’s consideration of the claims in this                 
              application has been limited to claim 1.  However, claim 12, another independent claim, is                  
              broader than claim 1.  This is seen in that the rejection posited by the examiner relies upon               
              Maniatis for its description of so-called “conventional differential hybridization techniques.”             

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