And Appeal No 94-1146 Application 07/746,050 isolated from soil collected in Uruguay (Spec., p. 3, last paragraph). 2. The rejections A. Claims 1-12 stand rejected under 35 U.S.C. § 103 as being unpatentable in view of antibiotic AB-85 disclosed in Japanese Patent Publication 59-18035, published April 25, 1984. B. Claims 1-12 stand provisionally rejected for obviousness-type double patenting of Claims 1-9 of commonly assigned copending Application 07/747,456. C. Claims 1-12 stand provisionally rejected for obviousness-type double patenting of Claims 1-9 and 11 of commonly assigned Application 07/746,059. 3. Discussion A. Obviousness under Section 103 The examiner has the initial burden of making out a case for obviousness under 35 U.S.C. § 103. Here, the examiner’s case for obviousness is supported by the following arguments (Examiner’s Answer, pp. 3-4): The Japanese patent discloses an antibiotic having molecular formula C H N O . Appellants on 25282 5 page 13 of the specification state that the macrolactam monosaccharide of formal [sic, formula] 2 and having the molecular formula as given, is disclosed by the - 3 -Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007