Ex parte RAIKHEL et al. - Page 17




          Appeal No. 94-2232                                                          
          Application 07/888,367                                                      


          expectation of success in view of the cited prior art.  See In              
          re O’Farrell,                                                               
          853 F.2d at 903, 7 USPQ2d at 1681 (“For obviousness under §                 
          103, all that is required is a reasonable expectation of                    
          success.”)                                                                  
          The examiner predicts (Ans., p. 12, l. 12-17):                              
               Thus, one of ordinary skill in the art would have kept                 
               probing until encountering the intact terminator (i.e.,                
               including polyadenylation signal) and such a sequence                  
               would have inherently encoded the rest of the naturally                
               encoded previously unknown polypeptide portion C-terminal              
               to the N-terminal 43 amino acid sequence which was known.              
          The position taken by the examiner falls from its own weight.               
          Since the examiner admits that the C-terminal position of the               
          protein in question was “unknown” at the time of the present                
          invention, it is not clear why one of ordinary skill in the                 
          art would have had reason to look for it, let alone a                       
          reasonable expectation of finding it.  This is not obviousness              
          within the meaning of 35 U.S.C. § 103.  This is surprise which              
          is more indicative of patentability.                                        
               B.   Rejections under 35 U.S.C. § 102(f) and § 103                     
               But for the fact that the claimed subject matter in In re              
          Katz, 687 F.2d 450, 215 USPQ 14 (CCPA 1982), was rejected                   

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