Appeal No. 95-3911
Application No. 08/189,124
tissue exhibit a fluorescence at a color substantially
different from the light pink appearance of normal tissue.
Optical equipment and techniques are used to measure this
fluorescence.
In summary, both Makino and Modell sense fluorescent
light emitted from an object in a sample cell. The examiner
recognizes (Answer, pages 3 and 4) that Makino and Modell use
a “backscattering geometry” as opposed to a “transmission
geometry” as disclosed and claimed by appellants. Appellants
have not challenged the examiner’s conclusion (Answer, pages 3
and 4) that it would have been obvious to one of ordinary
skill in the art to use a “transmission geometry” in both
Makino and Modell in lieu of the “backscattering geometry.”
Yoo discloses techniques for improving the signal-to-
noise ratio of an image formed of an object hidden in or
behind a semi-opaque random media. In the disclosed
techniques, the ballistic or unscattered portion of a pulse is
the signal, and the scattered portion of the pulse is the
noise. One of the techniques disclosed by Yoo involves the
introduction of an absorbing dye into a random medium to
reduce the noise or multiple scattered light (column 8, lines
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