Ex parte WALDER - Page 4




                 Appeal No. 95-4669                                                                                                                     
                 Application 08/044,674                                                                                                                 


                 “high” water sorption.  Examples of soft polymers having “low” water sorption are SR                                                   
                 (silicone rubber(cross linked)), PU (polyurethane rubber), and PVC (poly (vinyl                                                        
                 chloride)).  Uses of such polymers include tubes, diaphragms, coatings, implants,                                                      
                 pacemakers, adhesives, and blood bags.  An example of a soft polymer having “high”                                                     
                 water sorption is PHEMA (poly (hydroxyethyl methacrylate)).  Uses of such polymers                                                     
                 include contact lenses, burn dressings, and coatings.  On page 18, Hoffman indicates                                                   
                 that the water sorption of PU (polyurethane) is in the range of 1-5%.                                                                  
                                                                                                               3                                        
                          Independent claim 1 calls for an article comprising a hydrophilic  polymer having                                             
                                  4                            5                                                                                       
                 an insoluble  silver bulk distributed  therein, with the polymer having a water absorption                                             
                 of 5% or more by weight.  Independent claim 2 contains similar limitations.                                                            
                          In rejecting claims 1 and 2, and claims 3-5 that depend from claim 2, as being                                                




                          3Appellant’s specification expressly states on page 2 that, in the present                                                    
                 application, the term “hydrophilic” means “having a water absorption of 5% or more by                                                  
                 weight.”                                                                                                                               
                          4Read in light of the supporting specification, it is clear that the term “insoluble”                                         
                 as used here does not mean zero solubility, but rather very low solubility such that the                                               
                 active agent (e.g., silver) leaches out slowly during use.  See, for example, page 7 of                                                
                 the specification (“The silver chloride in the catheter of the invention is leached slowly                                             
                 because of the very low solubility of the salt.  This slow leach rate . . . has the                                                    
                 advantage of providing anti-infective activity of long duration.”).                                                                    
                          5Appellant’s specification expressly states on page 2 that, in the present                                                    
                 application, the term “bulk distributed” means “substantially evenly distributed                                                       
                 throughout the polymer.”                                                                                                               
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