Ex parte KOLB et al. - Page 8




                 Appeal No. 96-0401                                                                                       Page 8                        
                 Application No. 08/127,304                                                                                                             


                 prior art or by knowledge generally available to one of                                                                                
                 ordinary skill in the art, that would have suggested to one of                                                                         
                 ordinary skill in the art at the time the invention was made                                                                           
                 to omit the apertures (42) from the holding tray (24).                                                                                 
                 Instead, it appears to us that the examiner relied on                                                                                  
                 impermissible hindsight in reaching the determination that it                                                                          
                 would have been obvious to one of ordinary skill in the art to                                                                         
                 make the holding tray from a solid plate without holes for the                                                                         
                 extended storage and analysis of biological samples.                                                                                   


                          Since all the limitations  are not taught or suggested by3                                                                                
                 the applied prior art, we will not sustain the 35 U.S.C. § 103                                                                         






                          3We note that the claimed holding tray recited in claim 1                                                                     
                 is not readable on Manns' base enclosure 26.  While Manns'                                                                             
                 base enclosure 26 does have a bottom wall without holes, the                                                                           
                 bottom wall of Manns' base enclosure 26 is not adjacent (as                                                                            
                 disclosed in the appellants specification adjacent encompasses                                                                         
                 either the filter medium abutting the bottom wall of the                                                                               
                 holding tray or the filter medium abuts a thin, i.e.,                                                                                  
                 thickness ranging from 0.005 inches to 0.020 inches, crosstalk                                                                         
                 shield which abuts the bottom wall of the holding tray) to the                                                                         
                 lower surface of the filter sheet 22 as shown in Figure 5.                                                                             







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