Appeal No. 97-2359 Application 07/894,260 distribution”. What is recited is “substantially mono- dispersed particle size”. In view of appellants’ specification, it appears that “substantially mono-dispersed particle size” has the same meaning as “substantially uniform particle size distribution” and “substantially uniform size” (page 1, line 19; page 7, lines 1, 19-20 and 24). Appellants, however, do not state what is meant by “substantially” in any of these terms. Whitehead teaches that if the ratio of divalent to trivalent iron salts used to form the oxide particles is too low, the particle size becomes more heterogeneous, but the particles nevertheless can be silanized (col. 11, lines 44- 51). This teaching indicates that uniformity of particle size is a result-effective variable and that particles having a uniform particle size are desirable. Thus, in view of this teaching, it would have been prima facie obvious to one of ordinary skill in the art to use conventional techniques to obtain a substantially uniform particle size, with the optimum particle size distribution being determined through no more than routine experimentation. See In re Boesch, 617 F.2d 272, -5-5Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007