Ex parte BUSCEMI - Page 11




          Appeal No. 97-2552                                        Page 11           
          Application No. 08/541,658                                                  


          material comprises a structure with at least a portion of the               
          structure formed by a crosslinking agent such that upon irradi-             
          ation of the suture material the crosslinking agent adheres to              
          the biological material and thereby provides closure at the                 
          anastomotic site.  The laser means 83 provides the necessary                
          light energy in the form of laser radiation to effect                       
          crosslinking of the suture material at the anastomotic site.                
          Sinofsky '677 teaches (column 2, lines 52-61) that various                  
          "biological glue" materials can be employed as crosslinking                 
          agents in either solid, liquid, gel or powder form to form a bond           
          to tissue segments and thereby hold them together while natural             
          healing processes occur.  Examples of such crosslinking agents              
          include collagen, elastin, fibrin, albumin and various other                
          photoreactive polymeric materials.  In addition, Sinofsky '677              
          (column 3, lines 16-21) uses the terms "anastomosis" and                    
          "anastomotic site" to broadly encompass the joinder of biological           
          structures, including, for example, incision and wound healing,             
          repair of blood vessels and other tubular structures, sealing of            
          fissures, nerve repairs, reconstructive procedures, and the like.           


               Thomas discloses at column 5, lines 21-23, that light rod 16           
          of his dental curing light gun could employ a liquid light guide.           








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