Ex parte HANSON et al. - Page 18




                 Appeal No. 94-3255                                                                                                                     
                 Application 07/673,264                                                                                                                 


                 include, inter alia, Bacillus)- are microorganisms which can                                                                           
                 utilize methanol, methylamine or both as a source of carbon                                                                            
                 and energy.   Specification, p. 1, lines 29-37.  The9                                                                                                                  
                 specification further discloses that a “preferred nutrient                                                                             
                 media for culturing the bacterium [sic, bacteria] of the                                                                               
                 present invention to produce amino acids includes a carbon and                                                                         
                 energy source, preferably methanol....”  Id., p. 3, lines 28-                                                                          
                 32.  The specification does not describe any other compounds                                                                           
                 as carbon and energy sources for the claimed methylotrophs                                                                             
                 (emphasis added).  Thus, while the claim language is “open” to                                                                         
                 other carbon and energy sources, it appears to be open in a                                                                            
                 very limited sense, to the further inclusion of methylamines                                                                           
                 only.                                                                                                                                  
                          As to our colleague's conclusion (subsection (iii) above)                                                                     
                 that the phrase “excreting at least about 5 g/l of lysine,                                                                             
                 aspartic acid, phenylalanine, or tryptophan,” is indefinite,                                                                           
                 we disagree.  In view of the use of the conjunctive “or,” we                                                                           


                          9The specification also describes obligate methylotrophs                                                                      
                 as microorganisms which utilize methane as a source of carbon                                                                          
                 and energy.  However, since all these microorganisms are said                                                                          
                 to be gram-negative, this group does not include the gram-                                                                             
                 positive microorganisms of the genus Bacillus.                                                                                         
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