Ex parte BONAVENTURA et al. - Page 4




          Appeal No. 95-1779                                                          
          Application 07/683,130                                                      
               hindering attachment of said organism to said surface by               
               interfering with said organisms mechanisms for attachment              
               to submerged surfaces.                                                 
                    27. A method for preventing fouling of an aquatic                 
               apparatus by an aquatic organism without contamination of              
               the environment, which comprises:                                      
                    coating a surface of said apparatus with a                        
          composition                                                                 
               containing an inert matrix and a biologically active                   
          enzyme                                                                      
               chemically bonded to said inert matrix, wherein said                   
          enzyme                                                                      
               is capable of hindering attachment of said organism to                 
          said                                                                        
               surface while coated on said surface, wherein said                     
          apparatus                                                                   
               is one member selected from the group consisting of ship               
               hulls, pilings, glass and other transparent observation                
               windows, sonar domes, water-conducting pipes, cooling                  
                    towers, ponds, pumps, and valves.                                 


                                     Discussion                                       
          1.   Section 103 in view of Christie’s teaching                             
               With regard to the teaching in Christie’s Abstract, the                
          examiner acknowledges (Examiner’s Answer (Ans.), p. 4):                     
                    While the reference suggests the use of an enzyme                 
               system in combination with paint marine coatings, the                  
               reference is silent as to how the enzyme system is                     
               incorporated into the coating.                                         
          However, the examiner maintains the rejection because (Ans.,                
          pp. 4-5, bridging para.):                                                   
                    . . . it is notoriously well known in the art to                  
               immobilize enzymes on a solid surface so as to be in                   
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