Appeal No. 95-2220 Application No. 08/059,682 That calcium has been used in a method treating individuals having symptoms associated with PMS is not contested by appellant, and is factually established by the disclosures in the Thys-Jacobs reference. However, we agree with appellant that the Yamato reference fails to provide an adequate factual basis to establish that vitamin D has been used to treat individuals having symptoms associated with PMS (i.e., the same purpose). While Yamato teaches that vitamin D may be used to treat patients suffering from hypertension, there is no disclosure of record that hypertension involves a symptom or symptoms associated with PMS. Indeed, appellant correctly points out that hypertension is not a symptom of PMS (brief, unnumbered page 3), and we take official notice that 2 hypertension is a disease involving high blood pressure while premenstrual tension involves nervousness, mental irritability, and depression preceding menstruation. Further, we find that Yamato’s reference to the use of vitamin D dosages for treating “pains” is too general a teaching to suggest the treatment of PMS symptomatology. 2See Stedman’s Medical Dictionary, 24th Edition pages 676, 677, and 1417, copyright 1982, copy attached. 3Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007