Appeal No. 95-2743
Application 08/023,016
Claims 1, 2 and 4 are illustrative of the subject matter on appeal and read as
follows:
1. A method for treating neurodegenerative diseases or disorders which
comprises administering to a mammal in need a therapeutically effective amount of a
compound selected from ralitoline, phenytoin, lamotrigine, carbamazepine, lidocaine or
tetrodotoxin.
2. A method for treating neurodegenerative
diseases or disorders which comprises administering
to a mammal in need a therapeutically effective
amount of a compound of formula
wherein A is 4-pyridinyl; R and R are independently halogen, lower alkyl, lower alkoxy, or1 2
nitro, and R is hydrogen, halogen, lower alkyl, lower alkoxy, or nitro, or a pharmaceutically
3
acceptable acid addition salt thereof.
4. A method according to Claim 2 wherein the neurodegenerative disorder is
acute brain injury.
The references relied on by the examiner are:
Lobbestael et al. (Lobbestael) 4,629,731 Dec. 16, 1986
Berkow, The Merck Manual of Diagnosis and Therapy (Merck Manual), Fourteenth
Edition, Merck Sharp & Dohme Research Laboratories, Rahway, N.J., pp. 1304-13
(1982).
The references relied on by the appellants are:
2
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