Ex parte WANG et al. - Page 4




              Appeal No. 95-3268                                                                                           
              Application 07/521,695                                                                                       


                     Anticipation requires the disclosure, in a single prior art reference, of each element                
              of the claim under consideration. W.L. Gore & Assoc. v.Garlock, Inc., 721 F.2d 1540,                         
              1554, 220 USPQ 303, 313 (Fed. Cir. 1983), cert. denied, 469 U.S. 851 (1984).  In                             
              considering Aston (I), we note particularly Example A, which discloses the administration                    
              of a human growth hormone and antibody combination to non-human vertebrate.  The                             
              observed results, over a period of three weeks, included increased weight gain in the thus                   
              treated mice as compared to the control given no growth hormone or given growth                              
              hormone without the antibody.  This example would reasonably appear to meet all                              
              limitations of claim 23 and establish a prima facie case of anticipation of the claimed                      
              subject matter with regard to claims 23-25.                                                                  
                     In rebuttal, appellants argue that the reference fails to disclose the limitations of                 
              claim 23, which require "potentiating the activity of a somatotropin over prolonged periods                  
              of time" and "such that the weight of the vertebrate [, non-human] continues to exceed that                  
              of a vertebrate [, non-human] treated with the same amount of said somatotropin alone                        
              over a given period of time." (reply brief, page 3).  Where functional language is used, it is               

              appropriate to look to the specification for guidance in determining the finite amounts                      
              which correspond to the functional language.  See In re Woodruff, 919 F.2d 1575, 1577,                       
              16 USPQ2d 1934, 1936 (Fed. Cir. 1990); In re Herz, 537 F.2d 549, 551, 190 USPQ 461,                          
              463 (CCPA 1976).   We find nothing in the specification which would define or limit this                     


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