Ex parte HENDLEY et al. - Page 8




             Appeal No. 95-3640                                                                                   
             Application 08/147,742                                                                               


             examiner has not explained, and we do not find, why one of                                           
             ordinary skill in the art could not have carried out, without                                        
             undue experimentation, the method recited in appellants’ claim                                       
             1 as that claim is interpreted above, or in appellants’ claim                                        
             4 which recites a method for protecting against infection by                                         
             rhinoviruses.  Hence, we reverse the rejection of claims 1-6                                         
             under 35 U.S.C. § 112, first paragraph.                                                              
                                    Rejection under 35 U.S.C. § 103                                               
                    Merck Index discloses that ethanol was a known topical                                        
             anti-infective.  Mazur discloses that a mixture of 3% iodine,                                        
             2% Mercurochrome, 10% phenol and 47.5% ethanol showed the                                            
             highest virucidal activity of ten disinfectants and                                                  
             antiseptics tested in vitro against polio type I, vesicular                                          
             stomatitis, vaccinia and adeno-viruses.  Anderson discloses                                          
             that diseases caused by infections with bacteria, virus and                                          
             fungi were cured by combined or separate application of acids                                        
             and salts.  Specifically, Anderson states that                                                       
             “[a]dministration of benzoic acid (or Na benzoate) and citric                                        
             acid inhibited the outbreak of Herpes labialis.”  Kirschner                                          
             discloses that disinfectants comprising citric acid and,                                             


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