Appeal No. 95-4435 Application No. 07/833,146 The oligonucleotides may be used in vitro or in vivo for modifying the phenotype of cells, or for limiting the proliferation of pathogens such as viruses, bacteria, protists, Mycoplasma species, Chlamydia or the like, or for inducing morbidity in neoplastic cells or specific classes of normal cells. Manifestly, the specification describes in vitro utilities, contrary to the examiner's characterization. Where, as here, a legal conclusion of non-enablement is based on clearly erroneous fact-finding, the legal conclusion cannot stand. Furthermore, the Examiner's Answer is internally inconsistent and procedurally flawed. In the Answer, page 2, sections (7) and (8), the examiner states that no prior art of record is relied on, nor is any new prior art cited or relied on in rejecting the appealed claims. Nevertheless, in the Examiner's Answer, paragraph bridging pages 6 and 7, and in the first full paragraph of page 7, the examiner makes reference to the "Ulhmann et al." publication. In the Examiner's Answer, the examiner does not provide a citation for "Ulhmann et al.," nor is it clear from the record just what this publication is. Apparently, the examiner does rely on it. This, in and of itself, constitutes reversible error. -4-Page: Previous 1 2 3 4 5 6 7 NextLast modified: November 3, 2007