Appeal No. 1996-0944
Application No. 08/181,259
Marchi et al. (Marchi) 4,341,785 Jul. 27, 1982
Swedberg et al. (Exhibit A), “Comparison of Single-Dose vs One-Week Course of
Metronidazole for Symptomatic Bacterial Vaginosis,” 254 Journal of the American Medical
Association 8, 1046-1049 (Aug. 23/30, 1985).
J. McCue (Exhibit B), “Evaluation and Management of Vaginitis: An Update for Primary Care
Practitioners,” 149 Archives of Internal Medicine, 565-568 (March 1989).
Durfee et al. (Exhibit C), “Ineffectiveness of Erythromycin for Treatment of Haemophilus
vaginalis-Associated Vaginitis: Possible Relationship to Acidity of Vaginal Secretions,” 16
Antimicrobial Agents and Chemotherapy 5, 635-637 (November 1979).
B. Majeroni (Exhibit D), “New Concepts in Bacterial Vaginosis,” 44 AFP 4, 1215-1218
(October 1991).
Physicians’ Desk Reference (Exhibit E), 47th ed., pages 927-928:METROGEL-VAGINAL
(1993).
Treherne et al. (Exhibit F), “In Vitro Studies of Chlamydia trachomatis Susceptibility and
Resistance to Rifampin and Rifabutin,” 33 Antimicrobial Agents and Chemotherapy 8, 1393-1394
(August 1989).
Martindale The Extra Pharmacopoeia, Thirteenth Edition, page 200:Rifaximin (1993).
The references relied upon by this Merits Panel are:
Curtis-Prior et al. (Curtis-Prior) 4,804,674 Feb. 14, 1989
Egidio et al. (Egidio) 5,314,904 May 24, 1994
(filed Jun. 16, 1992)
ISSUES
Claims 24-30 stand rejected under 35 U.S.C. § 103 as being unpatentable over Parenti in view
of Merck and Remington. We reverse.
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