Ex parte KAMIYAMA et al. - Page 11




                   Appeal No. 1996-2015                                                                                                                           
                   Application No. 08/181,539                                                                                                                     


                   In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d 1443, 1444 (Fed. Cir. 1992).  Appellants argue                                                   

                   unexpected results, i.e., the claimed apparatus results in a 2.5 fold decrease in the distribution range of                                    

                   particles produced (brief, pages 16-19).                                                                                                       

                            Having reviewed the showing in the specification, we agree with the examiner that appellants                                          

                   have not met their burden of showing unexpected results.  First, appellants have not compared the                                              

                   claimed subject matter with the closest prior art, i.e., the gear pump mixer apparatus of Lee, or                                              

                   explained why the evidence in the specification based upon a four-blade impeller proves a comparison                                           

                   of their claimed invention which is closer that than Lee.                                                                                      

                   In re Baxter Travenol Labs., 952 F.2d 388, 392, 21 USPQ2d 1281, 1285 (Fed. Cir. 1991); In re                                                   

                   De Blauwe, 736 F.2d 699, 705, 222 USPQ 191, 196 (Fed. Cir. 1984).  Second, it is not enough for                                                

                   appellants to show that the results for appellants'  claimed invention and the comparative examples are                                        

                   different.  Appellants have the burden of showing that the differences are significant and unexpected.  In                                     

                   re Freeman, 474 F.2d 1318, 1324, 177 USPQ 139, 143 (CCPA 1973);  In re D'Ancicco, 439 F.2d                                                     

                   1244, 1248, 169 USPQ 303, 306 (CCPA 1971).  For example, a four-blade impeller mixer would                                                     

                   not be expected to provide the incremental mixing and, therefore, “perfect” mixing of Lee’s gear pump                                          

                   mixer (col. 7, lines 33-51).  Alternatively, the results may not be unexpected in view of the improved                                         

                   efficiency in homogenization based upon use of centrifugal force and roughened working surfaces                                                

                   suggested by China and Eppenbach ‘178, respectively.                                                                                           


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