Appeal No. 1996-3980 Application 08/290,125 sufficiently to have placed a person of ordinary skill in the art in possession of this composition, thus anticipating claim 1 under § 102(b). In re Spada, 911 F.2d 705, 708, 15 USPQ2d 1655, 1657 (Fed. Cir. 1990). Indeed, as seen from Maruno Example 1 and complexes No. 2 through 7 of Maruno Table 2, Maruno Example 2 and complexes No. 15 and 18 through 21 of Maruno Table 4, and Maruno Example 3 and Maruno Table 5, the magnetic complexes disclosed by Maruno can comprise about 44 to 62 weight percent of polysaccharide carboxyalkyl ethers in which about 25 to 42 weight percent of magnetic iron oxide particles of about 6 to 10 nm are dispersed, which compositions are recovered as a powder by freeze drying. One of ordinary skill in this art would have reasonably expected that the polysaccharide carboxyalkyl ethers and the magnetic iron oxide particles are chemical bonded, as taught by Maruno (col. 10, lines 16-19), and that at least a portion of the ferrous chloride used in the preparation of the complexes would form magnetite, that is, Fe O , as taught by Maruno 3 4 (col. 4, lines 15-16). Thus, it reasonably appears that the complexes comprise at least a polysaccharide carboxyalkyl ether as “a resin” that contains “uniformly dispersed” “nanocrystalline particles of Fe O ” that are “bonded” thereto, wherein the “resin” and the “nanocrystalline particles of 3 4 Fe O ” are present in certain weight percent such that the complexes are encompassed by claim 1. 3 4 Accordingly, because the chemically bound complexes of carboxyalkyl ethers of polysaccharides and magnetic iron oxide particles reasonable appear to be identical to the magnetic nanocomposite compositions of claim 1, the burden falls upon appellants to establish by effective argument and/or objective evidence that the claimed invention patentably distinguishes over this reference with respect to . See Spada, 911 F.2d at 708-09, 15 USPQ2d at 1657-58; In re Best, 562 F.2d 1252, 1254-56, 195 USPQ 430, 432-34 (CCPA 1977). We have reassessed the patentability of the claimed invention encompassed by claim 1 based on the totality of the record, including all the factual evidence of anticipation in Maruno and appellants’ arguments evidence that the reference is not anticipatory, giving due consideration to the weight of appellants’ arguments. We have carefully considered appellants’ arguments with respect to the difference in water solubility and the affect on viscosity properties of aqueous mixtures between the polysaccharide carboxyalkyl ether containing magnetic complexes of Maruno and the “ion exchange resins of the - 6 -Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007