Ex parte MURAMATSU et al. - Page 8




          Appeal No. 1997-1430                                                        
          Application No. 08/225,756                                                  


          or mechanical equivalents.  In re Ruff, 256 F. 2d 590, 118                  
          USPQ 340 (CCPA 1958).                                                       
               With respect to the Examiner’s second obviousness                      
          rationale, however, we are of the view that the Examiner’s                  
          analysis has at least satisfied the burden of presenting a                  
          prima facie case of obviousness.  In other words, the Examiner              
          has pointed out the prior art teachings of Fujihira and                     
          Betzig, has reasonably indicated the perceived differences                  
          between the prior art and the claimed invention set forth in                
          independent claims 14, 21, and 28, and has provided reasons                 
          (Answer, page 5, section B) as to how and why the Fujihira’s                
          microscope would be modified by the substitution of the hook-               
          shaped probe of Betzig to arrive at the claimed invention.                  
               After reviewing Appellants’ arguments in response, it is               
          our opinion that, to the extent any arguments have been                     
          directed to the issue of the combinability of Fujihira and                  
          Betzig, we find such arguments to be unpersuasive in                        
          overcoming the Examiner’s prima facie case of obviousness.                  
          Appellants’ arguments in the Briefs regarding the merits of                 
          the teachings of Betzig center on the contention that Betzig’s              
          probe is a shear-force detecting probe rather than a light                  
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