Ex parte COLE et al. - Page 4




          Appeal No. 98-0573                                                           
          Application 08/418,055                                                       


          appellants’ claims (answer, page 4).                                         
               This argument is not persuasive because the examiner has                
          not established that those of ordinary skill in the art were                 
          aware that clavulanic acid or the salts thereof recited in                   
          appellants’ claims were known in the art to be to be among the               
          “other antibiotic substances” mentioned in Lilly or to have                  
          any other                                                                    




          use.  Thus, it is not apparent from the record why one of                    
          ordinary skill in the art would have been motivated to purify                
          these compounds.  The record indicates that the motivation                   
          relied on by the examiner for purifying clavulanic acid or its               
          salts comes solely from appellants’ specification.  Hence, the               
          examiner’s rejection is based on impermissible hindsight.  See               
          W.L. Gore & Associates v. Garlock, Inc., 721 F.2d 1540, 1553,                
          220 USPQ 303, 312-13 (Fed. Cir. 1983); In re Rothermel, 276                  
          F.2d 393, 396, 125 USPQ 328, 331 (CCPA 1960).  Accordingly, we               
          do not sustain the rejection under 35 U.S.C. § 103.                          
                                       DECISION                                        


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