Appeal No. 2000-0320 Page 6
Application No. 08/480,082
require (1) a first sprayer containing an aqueous solution of
chitosan and a complexing agent; (2) a second sprayer
containing an aqueous solution of alginate; and (3) an
actuator which causes the first sprayer and the second sprayer
to spray.
Viegas discloses medical uses of in situ formed gels.
Specifically, Viegas discloses that balanced pH, hyperosmotic,
hypoosmotic, or isoosmotic gels are ideal vehicles for drug
delivery since they are especially suited for topical body
cavity or injection application of drugs or diagnostic agents;
for drug or diagnostic agent delivery to the eye of a mammal;
as protective corneal shields; or as ablatable corneal masks
useful in laser reprofiling of the cornea. Viegas also
discloses that the compositions without the addition of a drug
or diagnostic agent are useful as medical devices, for
instance, in separating surgically or otherwise injured tissue
as a means of preventing adhesions.
Viegas teaches (column 5, lines 23-31) that the
compositions of his preferred embodiment comprise aqueous
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