Appeal No. 2000-1779 Application No. 08/473,204 rat GluR6 receptor subunit was found by the examiner to be 99.5% identical to the amino acid sequence of the receptor subunit of the appealed claims. The examiner references (Answer, bridging paragraph, pages 4-5) Sun and Puckett for a description of the isolation of a DNA encoding human homolog of the rat GluR1. The examiner further references (Answer, page 6) Puckett for the teaching that “[t]he extreme conservation between the human and rat kainate receptor subunits suggest that a similar gene family will encode human kainate receptors.” While the claims on appeal are drawn to “[a] method of detecting interaction” using a human EAA4 (having a specific SEQ ID NO.) receptor-producing cell. It is obviously essential to the examiner’s rejection that a cDNA encoding the EAA4a or 4b receptor must first be successfully isolated. Once isolated the cDNA is used to engineer a cell to express the receptor, and then the claimed method can be performed. With regard to the examiner’s approach, we note that the instant application is a divisional application of Application No. 07/903,456, now United States Patent No. 5,574,144 (‘144). It appears that the examiner’s rejection of the claims in the present application under 35 U.S.C. § 103 is inconsistent with the determination that at least claims 1, 3, 15, 16 and 18 of ‘144 are patentable. 23Page: Previous 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 NextLast modified: November 3, 2007