Interference No. 103,625
___________
FINAL DECISION
Before WINTERS, DOWNEY and WILLIAM F. SMITH, Administrative Patent Judges.
DOWNEY, Administrative Patent Judge.
This interference involves a patent to LeMaire et al. (LeMaire), U.S. Patent
No. 5,344,915, assigned to BASF Aktiengesellschaft, and an application to Wallach et al.
(Wallach), Serial No. 07/930,443, assigned to Yeda Research and Development Co. Ltd.
The subject matter at issue is specific tumor necrosis factor binding proteins
having specific N-terminal amino acid sequences and is defined by a single bifurcated
count which reads as follows:
Count 1
a) An isolated and purified Tumor Necrosis Factor (TNF) binding protein
(TBPII) having the following characteristics:
i. an N-terminal amino acid sequence: Xaa-Pro-
Tyr-Ala-Pro-Glu-Pro-Gly-Ser-Thr, where Xaa consists of the following
amino acid sequences: Thr, Val-Ala-Phe-Thr-, and Phe- Thr;
ii. the ability to inhibit the cytotoxic effect of TNF-" on murine A9 cells;
iii. a molecular weight of about 30kd in reducing SDS-PAGE analysis.
or
b) A purified and isolated TNF"-binding protein which has a molecular
weight of about 42,000 daltons and has at the N terminus the amino acid sequence
2
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