Appeal No. 1996-2240
Application No. 08/105,482
Appendix A
Claims 1, 10, 21, 22 and 27
1. In a method for screening disorders in a test patient in which biological
samples containing electrochemically active molecular constituents from
normal, unafflicted control individuals, afflicted, abnormal individuals, and
said test patient are electrochemically analyzed to generate electrical signal
patterns representative of said electrochemically active molecular
constituents of said samples, the improvement which comprises creating a
data base of electrical signal patterns representative of the frequency
distribution of a plurality of predetermined electrochemically active
constituents of biological samples from an epidemiologically significant
number of individuals having known categories of disorders and from said
unafflicted control individuals, comparing said electrical signal patterns in
said data base for conformity to electrical signal patterns representative of
the frequency distribution of said predetermined constituents of a fluid
sample from said test individual, and diagnosing a disorder in said test
patient based upon said comparison.
10. A method according to claim 1, wherein each electrical signal pattern
representative of frequency distribution of constituents of said biological
samples is generated by the following steps, comprising:
passing each one of said biological samples separately through a
liquid chromatographic column for achieving time-space separation
of said constituents of said biological sample eluting in the column
and an electrochemical detection apparatus for generating electrical
signals representative of the electrochemical pattern of said
biological sample.
21. A method according to claim 10, wherein said constituents of said
biological samples are separated by electrochemical characteristics in said
electrochemical detection apparatus.
22. A method for screening disorders in a living subject organism, and
including electrochemically analyzing biological samples including
18
Page: Previous 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Next
Last modified: November 3, 2007